

Consequently, somatosensation can deteriorate, which is an enormous risk factor for the development of diabetic foot ulcerations. It is possible that the effect of SEN on thick, myelinated Aβ-fibers is only marginally present.ĭiabetes mellitus is a disease that may lead to degeneration processes in nerve fibers, as well as structural and quantitative changes in mechanoreceptors. However, the descriptively reduced variations in experiment 1 indicate that participants felt more consistently. Interestingly, taking into account the most severely affected (neuropathy severity) individuals, SEN seems to positively influence vibratory perception. SEN did not demonstrate improvements in VPT in diabetic individuals. CoV showed descriptively lower mean variations of 4 and 7% for VPT in experiment 1. We found no statistically significant effects of SEN on VPT and CoV ( p > 0.05).

Wilcoxon signed-rank and t tests were used to test for differences in VPT and CoV within frequencies, between the conditions with and without SEN. Plantar measurements were taken at the metatarsal area with and without SEN stimulation. Vibration perception thresholds (VPT) and corresponding VPT variations (coefficient of variation, CoV) of two experimental groups with diabetes mellitus were determined using a customized vibration exciter (30 and 200 Hz). Accordingly, this study aimed to investigate the effect of SEN on vibration sensitivity in diabetes.

Diabetes and its neurodegenerative profile, such as marked decreases in foot sensitivity, highlights the potential benefits of SEN in such populations. Subliminal electrical noise (SEN) enhances sensitivity in healthy individuals of various ages.
